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Vaccinated C57BL/6 Mice Develop Protective and Memory T Cell Responses to Coccidioides posadasii Infection in the Absence of Interleukin-10

Hung, Chiung-Yu; Castro-Lopez, Natalia; Cole, Garry T. (Infection and Immunity;Vol. 82, No. 2, 2014-01-22)

High concentrations of lung tissue-associated interleukin-10 (IL-10), an anti-inflammatory and immunosuppressive cytokine, correlate with susceptibility of mice to Coccidioides spp. infection. In this study, we found that ...

Vaccine Immunity to Coccidioidomycosis Occurs by Early Activation of Three Signal Pathways of T Helper Cell Response (Th1, Th2, and Th17)

Hung, Chiung-Yu; Gonzalez, Angel; Wüthrich, Marcel; Klein, Bruce S.; Cole, Garry T. (Infection and Immunity;Vol. 79, No. 11, 2011-10-13)

We have previously reported that C57BL/6 mice vaccinated with a live, attenuated mutant of Coccidioides posadasii, referred to as the ΔT vaccine, are fully protected against pulmonary coccidioidomycosis. This model was ...

Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice

Wüthrich, Marcel; Gern, Benjamin; Hung, Chiung-Yu; Ersland, Karen; Rocco, Nicole; Pick-Jacobs, John; Galles, Kevin; Filutowicz, Hanna; Warner, Thomas; Evans, Michael; Cole, Garry T.; Klein, Bruce (The Journal of Clinical Investigation;Volume 121, Issue 2, 2011-01-04)

Worldwide rates of systemic fungal infections, including three of the major pathogens responsible for such infections in North America (Coccidioides posadasii, Histoplasma capsulatum, and Blastomyces dermatitidis), have ...

Validation of All-Sky Imager Technology and Solar Irradiance Forecasting at Three Locations: NREL, San Antonio, Texas, and the Canary Islands, Spain

Richardson, Walter; Cañadillas, David; Moncada, Ariana; Guerrero-Lemus, Ricardo; Shephard, Les; Vega-Avila, Rolando; Krishnaswami, Hariharan (2019-02-17)

Increasing photovoltaic (PV) generation in the world's power grid necessitates accurate solar irradiance forecasts to ensure grid stability and reliability. The University of Texas at San Antonio (UTSA) SkyImager was ...

Value stream mapping along the product development process

Dombrowski, Uwe; Ebentreich, David; Schmidt, Stefan (Proceedings of the 24th International Conference on Flexible Automation & Intelligent Manufacturing, 2014)

Today's business conditions are characterized by increased competition. Therefore enterprises have to cope with shorter product life cycles, higher product complexity and more product variants. The reaction of many enterprises ...

Value stream mapping and discrete event simulation applied to reduce waste in a company that manufactures a family of automotive parts

Silva, Tatiany M. da; Ferreira, Joao C. E. (Proceedings of the 24th International Conference on Flexible Automation & Intelligent Manufacturing, 2014)

Lean manufacturing seeks consistent and complete elimination of waste in order to optimize resources. However, the elimination of such waste in most cases is done through of trial and error, which usually entails more costs ...

Variability in the Capacity to Produce Damage-Induced Aldehyde Green Leaf Volatiles among Different Plant Species Provides Novel Insights into Biosynthetic Diversity

Engelberth, Jurgen; Engelberth, Marie (2020-02-06)

Green leaf volatiles (GLVs) are commonly released by plants upon damage, thereby providing volatile signals for other plants to prepare against the major causes of damage, herbivory, pathogen infection, and cold stress. ...

Variable production and indexical social meaning: On the potential physiological origin of intervocalic /s/ voicing in Costa Rican Spanish

Chappell, Whitney; Garcia, Christina (Studies in Hispanic and Lusophone Linguistics;10(1), 2017-05-02)

In several dialects of Spanish, men tend to exhibit more intervocalic /s/ voicing than women, e. g., oso ‘bear’ as [ozo], and this difference may have a physiological basis. File-Muriel et al. (2015, Disentangling the ...

Variations in the Morphology, Mechanics and Adhesion of Persister and Resister E. coli Cells in Response to Ampicillin: AFM Study

Uzoechi, Samuel C.; Abu-Lail, Nehal I. (2020-05-07)

Persister bacterial cells are great at surviving antibiotics. The phenotypic means by which they do that are underexplored. As such, atomic force microscope (AFM) was used to quantify the contributions of the surface ...