Now showing items 1-10 of 19
Vinyldiazo Reagents and Metal Catalysts: A Versatile Toolkit for Heterocycle and Carbocycle Construction
Over the past decade, vinyldiazo compounds have provided mild, efficient, and highly selective methods for the construction of heterocycles and carbocycles. Dinitrogen extrusion with suitable catalysts provides the carbon ...
Chiral donor−acceptor azetines as powerful reactants for synthesis of amino acid derivatives
(Nature Communications;, 2019-11-22)
Coupling reactions of amines and alcohols are of central importance for applications in chemistry and biology. These transformations typically involve the use of a reagent, activated as an electrophile, onto which nucleophile ...
Chemoselectivity in Dirhodium(II) Catalyzed Reactions of Diazoacetoacetates Prepared from α,β-Unsaturated Ketones
-Diazo β-keto esters from zinc triflate catalyzed Mukaiyama-Michael reactions between α,β unsaturated ketones and α silyloxyvinyldiazoacetates are valuable synthons for the synthesis of compounds that can be accessed through ...
Highly selective acylation of polyamines and aminoglycosides by 5-acyl-5-phenyl-1,5-dihydro-4H-pyrazol-4-ones
(Chemical Science;, 2017-08-30)
5-Acyl-5-phenyl-1,5-dihydro-4H-pyrazol-4-ones, accessible from arylpropargyl phenyldiazoacetates, are highly selective acyl transfer reagents for di- and polyamines, as well as aminoalcohols and aminothiols. As reagents ...
Oxidation of Hemoglobin and Myoglobin by Alkyl Nitrites. Inhibition by Oxygen
(Journal of Biological Chemistry;, 1981-12-10)
The reactions of human hemoglobin and sperm whale myoglobin with ethyl nitrite under aerobic conditions have been examined in kinetic detail. Ethyl nitrite converts two equivalents of oxyhemoglobin or oxymyoglobin to ...
Silver-Catalyzed Carbene Functionalization of Methane in Supercritical Carbon Dioxide
Formal [4+4]-, [4+3]-, and [4+2]-Cycloaddition Reactions of Donor-Acceptor Cyclobutenes, Cyclopropenes and Siloxyalkynes Induced by Brønsted Acid Catalysis
(Chemical Science;, 2021-02-18)
Brønsted acid catalyzed formal [4 + 4]-, [4 + 3]-, and [4 + 2]-cycloadditions of donor–acceptor cyclobutenes, cyclopropenes, and siloxyalkynes with benzopyrylium ions are reported. [4 + 2]-cyclization/deMayo-type ring-extension ...
Attempted Synthesis of Casbene by Intramolecular Cyclopropanation
The antifungal diterpene casbene has been prepared in low yield by intramolecular cyclopropanation of the vinyldiazomethane reactant formed from geranylgeraniol. Careful analysis of the reaction mixture revealed relatively ...
Cycloaddition reactions of enoldiazo compounds
(Chemical Society Reviews;, 2017-07-20)
Enoldiazo esters and amides have proven to be versatile reagents for cycloaddition reactions that allow highly efficient construction of various carbocycles and heterocycles. Their versatility is exemplified by (1) ...
Highly Efficient Olefin Isomerization Catalyzed by Metal Hydrides Derived from Dirhodium(II) Carboxylates and Catecholborane
(Main Group Metal Chemistry;, 1994-07-01)
Dirhodium(ll) tetraacetate in combination with catecholborane catalyzes the isomerization of alkenes and dienes. Effective isomerization occurs at 80-135°C with the use of only 0.1 mol % rhodium acetate. With 2-methyl-1, ...