Nanostructured materials as substrates for the development of biosensors

dc.contributor.advisorGarcia, Carlos D.
dc.contributor.authorAlharthi, Sarah
dc.contributor.committeeMemberBach, Stephan B.
dc.contributor.committeeMemberGorski, Waldemar
dc.date.accessioned2024-01-26T20:58:54Z
dc.date.available2024-01-26T20:58:54Z
dc.date.issued2012
dc.description.abstractThis thesis describes the experiments performed to evaluate the suitability of different types of electrodes towards the development of electrochemical biosensors. Commercial electrodes (electrodes containing carbon nanotubes and electrodes of indium tin oxide) were initially considered for detection of H2O2 (a byproduct of many enzymatic reactions) at low potentials in reduction mode. These electrodes did not show significant advantages with respect to traditional electrodes, even after selected surface modifications were performed. On the other hand, optically transparent carbon electrodes (fabricated by adsorption/pyrolysis of proteins) showed remarkable advantages towards the development of electrochemical biosensors. These electrodes were characterized by a combination of electrochemical, optical, and spectroscopic techniques. As a proof-of-concept, the optically transparent carbon electrodes were used as electrochemical transducers for the development of a glucose biosensor based on the oxidation of H2O2.
dc.description.departmentChemistry
dc.format.extent54 pages
dc.format.mimetypeapplication/pdf
dc.identifier.isbn9781267842435
dc.identifier.urihttps://hdl.handle.net/20.500.12588/2594
dc.languageen
dc.subject.classificationChemistry
dc.subject.classificationAnalytical chemistry
dc.subject.classificationBiochemistry
dc.titleNanostructured materials as substrates for the development of biosensors
dc.typeThesis
dc.type.dcmiText
dcterms.accessRightspq_closed
thesis.degree.departmentChemistry
thesis.degree.grantorUniversity of Texas at San Antonio
thesis.degree.levelMasters
thesis.degree.nameMaster of Science

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