In Vitro Interactions of Echinocandins with Triazoles against Multidrug-Resistant Candida auris

dc.contributor.authorFakhim, Hamed
dc.contributor.authorChowdhary, Anuradha
dc.contributor.authorPrakash, Anupam
dc.contributor.authorVaezi, Afsane
dc.contributor.authorDannaoui, Eric
dc.contributor.authorMeis, Jacques F.
dc.contributor.authorBadali, Hamid
dc.creator.orcidhttps://orcid.org/0000-0002-6010-8414en_US
dc.date.accessioned2023-07-14T18:45:35Z
dc.date.available2023-07-14T18:45:35Z
dc.date.issued2017-10-24
dc.description.abstractWe determined the in vitro interactions between echinocandins and azoles against 10 multidrug-resistant Candida auris strains by use of a microdilution checkerboard technique. Our results suggest synergistic interactions between micafungin and voriconazole with fractional inhibitory concentration index (FICI) values of 0.15 to 0.5, and we observed indifferent interactions when micafungin was combined with fluconazole (FICI, 0.62 to 1.5). Combinations of caspofungin with fluconazole or voriconazole exhibited indifferent interactions. No antagonism was observed for any combination.en_US
dc.description.departmentMolecular Microbiology and Immunologyen_US
dc.description.sponsorshipDepartment of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India; ESCMID; Mazandaran University of Medical Sciences, Sari, Iranen_US
dc.identifier.citationFakhim, H., Chowdhary, A., Prakash, A., Vaezi, A., Dannaoui, E., Meis, J. F., Badali, H. (2017). In Vitro Interactions of Echinocandins with Triazoles against Multidrug-Resistant Candida auris. Antimicrobial Agents and Chemotherapy, 61(11). doi:10.1128/aac.01056-17en_US
dc.identifier.issn1098-6596
dc.identifier.otherhttps://doi.org/10.1128/AAC.01056-17
dc.identifier.urihttps://hdl.handle.net/20.500.12588/1983
dc.language.isoen_USen_US
dc.publisherAmerican Society for Microbiologyen_US
dc.relation.ispartofseriesAntimicrobial Agents and Chemotherapy;Vol. 61, No. 11
dc.subjectin vitro interactionsen_US
dc.subjectazolesen_US
dc.subjectechinocandinsen_US
dc.subjectCandida aurisen_US
dc.titleIn Vitro Interactions of Echinocandins with Triazoles against Multidrug-Resistant Candida aurisen_US
dc.typeArticleen_US

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