Tinea nigra by Hortaea werneckii, a report of 22 cases from Mexico

Date
2008-06
Authors
Bonifaz, A.
Badali, Hamid
de Hoog, G. S.
Cruz, M.
Araiza, J.
Cruz, M. A.
Fierro, L.
Ponce, R. M.
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier; Westerdijk Fungal Biodiversity Institute
Abstract

Tinea nigra is a superficial mycosis caused by Hortaea werneckii. It is an infrequent asymptomatic infection that affects human palms and soles, and is mostly observed in tropical countries. We evaluate retrospectively twenty-two confirmed cases of tinea nigra from a total of eleven yr (1997–2007) and discuss the epidemiology, clinical features and treatment of this disease. In twelve cases, adults were involved, in 10, children. In nineteen cases the disorder was located on palms of hands and in three on soles of feet. In all cases, the obtained isolates were morphologically identified as Hortaea werneckii and the identification of ten isolates was retrospectively confirmed with the help of sequences of the internal transcribed spacer regions of the ribosomal DNA. The patients received topical treatment with Whitfield ointment, ketoconazole, bifonazole, or terbinafine. Treatment with keratolytic agents and topical antifungals was effective.

Description
Keywords
Hortaea werneckii, keratolysis, melanized fungus, superficial mycosis, tinea nigra, tinea palmaris
Citation
Bonifaz, A., Badali, H., de Hoog, G. S., Cruz, M., Araiza, J., Cruz, M. A., . . . Ponce, R. M. (2008). Tinea nigra by Hortaea werneckii, a report of 22 cases from Mexico. Studies in Mycology, 61(1), 77-82. doi:10.3114/sim.2008.61.07
Department
Molecular Microbiology and Immunology