Synthesis of Cellulose-Based Hydrogel—Nanocomposites for Medical Applications
| dc.contributor.author | Al-Tarawneh, Wala`a | |
| dc.contributor.author | Hamadneh, Imad | |
| dc.contributor.author | Tarawneh, Ola | |
| dc.contributor.author | Al Najdawi, Ali | |
| dc.date.accessioned | 2024-08-09T13:04:41Z | |
| dc.date.available | 2024-08-09T13:04:41Z | |
| dc.date.issued | 2024-07-31 | |
| dc.date.updated | 2024-08-09T13:04:41Z | |
| dc.description.abstract | This study focused on synthesizing a cellulose-based hydrogel nanocomposite as a green hydrogel by adding a microcrystalline cellulose (MC) solution to carboxymethyl cellulose sodium (CMC-Na) with citric acid as a cross-linker. Y<sub>2</sub>O<sub>3</sub> nanoparticles were incorporated during hydrogel preparation in different ratios (0.00% (0 mmol), 0.03% (0.017 mmol), 0.07% (0.04 mmol) and 0.10% (0.44 mmol)). FTIR analysis confirmed the cross-linking reaction, while XRD analysis revealed the hydrogels’ amorphous nature and identified sodium citrate crystals formed from the reaction between citric acid and CMC-Na. The swelling test in deionized water (pH 6.5) at 25 °C showed a maximum swelling percentage of 150% after 24 h in the highest nanoparticle ratio. The resulting cellulose hydrogels were flexible and exhibited significant antibacterial activity against <i>Staphylococcus aureus</i> (<i>S. aureus</i>) and <i>Escherichia coli</i> (<i>E. coli</i>). The synthesized cellulose-based hydrogel nanocomposites are eco-friendly and suitable for medical applications. | |
| dc.identifier | doi: 10.3390/polym16152183 | |
| dc.identifier.citation | Polymers 16 (15): 2183 (2024) | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12588/6602 | |
| dc.title | Synthesis of Cellulose-Based Hydrogel—Nanocomposites for Medical Applications |