In Vitro Activities of Eight Antifungal Drugs against 55 Clinical Isolates of Fonsecaea spp

Date

2010-04-01

Authors

Najafzadeh, Mohammad J.
Badali, Hamid
Illnait-Zaragozi, Maria Teresa
de Hoog, G. Sybren
Meis, Jacques F.

Journal Title

Journal ISSN

Volume Title

Publisher

American Society for Microbiology

Abstract

The in vitro activities of eight antifungal drugs against clinical isolates of Fonsecaea pedrosoi (n = 21), Fonsecaea monophora (n = 25), and Fonsecaea nubica (n = 9) were tested. The resulting MIC90s for all strains (n = 55) were as follows, in increasing order: posaconazole, 0.063 μg/ml; itraconazole, 0.125 μg/ml; isavuconazole, 0.25 μg/ml; voriconazole, 0.5 μg/ml; amphotericin B, 2 μg/ml; caspofungin, 2 μg/ml; anidulafungin, 2 μg/ml; and fluconazole, 32 μg/ml.

Description

Keywords

Fonsecaea

Citation

Najafzadeh, M. J., Badali, H., Illnait-Zaragozi, M. T., de Hoog, G. S., & Meis, J. F. (2010). In Vitro Activities of Eight Antifungal Drugs against 55 Clinical Isolates of Fonsecaea spp. Antimicrobial Agents and Chemotherapy, 54(4), 1636-1638. doi:10.1128/aac.01655-09

Department

Molecular Microbiology and Immunology