Microsatellite genotyping of clinical Candida parapsilosis isolates

dc.contributor.authorBadali, Hamid
dc.contributor.authorRezaie, Sassan
dc.contributor.authorMeis, Jacques F.
dc.contributor.authorAgha Kuchak Afshari, Setareh
dc.contributor.authorModiri, Mona
dc.contributor.authorHagen, Ferry
dc.contributor.authorMoazeni, Maryam
dc.contributor.authorMohammadi, Rasoul
dc.contributor.authorKhodavaisy, Sadegh
dc.creator.orcidhttps://orcid.org/0000-0002-6010-8414en_US
dc.date.accessioned2023-06-20T17:30:27Z
dc.date.available2023-06-20T17:30:27Z
dc.date.issued2017-12
dc.description.abstractBackground and Purpose: Candida parapsilosis is a predominant species found in nosocomial infection, particularly in hospitalized patients. The molecular epidemiology of the clinical strains of this species has not been well studied. The present study was performed with the aim of investigating the microsatellite genotyping of Candida parapsilosis among the Iranian clinical isolates. Materials and Methods: This study was conducted on 81 independent clinical C. parapsilosis isolates that were genotyped by using a panel of six microsatellite markers. Results: The short tandem repeat (STR) typing of clinical C. parapsilosis isolates demonstrated 68 separate genotypes, among which 57 genotypes were observed once and the remaining 11 cases were identified for multiple times. The Simpson’s diversity index for the panel of combined six markers yielded a diversity index of 0.9951. The heterogeneity was observed among the Iranian and the Netherlands clinical C. parapsilosis isolates. Conclusion: As the findings indicated, the clinical C. parapsilosis isolates from Iran showed a high genetic diversity. It can be concluded that molecular epidemiology could be useful for screening during outbreak investigation where C. parapsilosis is involved.en_US
dc.description.departmentMolecular Microbiology and Immunologyen_US
dc.description.sponsorshipTehran University of Medical Sciences & Health Servicesen_US
dc.identifier.citationBadali H, Rezaie S, Meis JF, Agha Kuchak Afshari S, Modiri M, Hagen F, Moazeni M, Mohammadi R, Khodavaisy S. Microsatellite genotyping of clinical Candida parapsilosis isolates. Curr Med Mycol. 2017 Dec;3(4):15-20. doi: 10.29252/cmm.3.4.15. PMID: 29707674; PMCID: PMC5917096.en_US
dc.identifier.issn2423-3420
dc.identifier.urihttps://hdl.handle.net/20.500.12588/1905
dc.language.isoen_USen_US
dc.publisherMazandaran University of Medical Sciencesen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subjectCandida parapsilosisen_US
dc.subjectgenotypingen_US
dc.subjectIranen_US
dc.subjectmicrosatelliteen_US
dc.titleMicrosatellite genotyping of clinical Candida parapsilosis isolatesen_US
dc.typeArticleen_US

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