GPLBrowse: An Interactive Platform Browser for NCBI GEO

Date
2007-12
Authors
Robbins, Kay A.
Burkhardt, Cory
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UTSA Department of Computer Science
Abstract

The variability in normalization and labeling of data in NCBI GEO and other publicly available databases is a barrier to large-scale data mining of microarray data. Because platform-wide summary tools are not available, researchers must download and curate data without an overview of the available samples. GPLBrowse is an interactive web tool for investigating the characteristics of samples and series for microarray platforms in NCBI GEO. The first release of GPLBrowse provides statistical overviews of all samples and series in the top 18 oligonucleotide microarray platforms of GEO. GPLBrowse allows users to select and save samples, search based on keywords, and view additional metadata or link to GEO. GPLBrowse uses an AJAX-based split-client-server architecture to achieve highly responsive user interaction.

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Department
Computer Science