In Vitro Activities of Luliconazole, Lanoconazole, and Efinaconazole Compared with Those of Five Antifungal Drugs against Melanized Fungi and Relatives
Date
2017-10-24
Authors
Shokoohi, Gholam Reza
Badali, Hamid
Mirhendi, Hossein
Ansari, Saham
Rezaei-Matehkolaei, Ali
Ahmadi, Bahram
Vaezi, Afsane
Alshahni, Mohamed Mahdi
Makimura, Koichi
Journal Title
Journal ISSN
Volume Title
Publisher
American Society for Microbiology
Abstract
The in vitro activities of novel azoles compared to those of five antifungal drugs against clinical (n = 28) and environmental (n = 102) isolates of black mold and melanized yeast were determined. Luliconazole and lanoconazole had the lowest geometric mean MICs, followed by efinaconazole, against tested isolates compared to the other drugs. Therefore, it appears that these new imidazole and triazole drugs are promising candidates for the treatment of infections due to melanized fungi and their relatives.
Description
Keywords
melanized fungi, in vitro, MIC, efinaconazole, lanoconazole, luliconazole
Citation
Shokoohi, G. R., Badali, H., Mirhendi, H., Ansari, S., Rezaei-Matehkolaei, A., Ahmadi, B., ... Makimura, K. (2017). In Vitro Activities of Luliconazole, Lanoconazole, and Efinaconazole Compared with Those of Five Antifungal Drugs against Melanized Fungi and Relatives. Antimicrobial Agents and Chemotherapy, 61(11). doi:10.1128/aac.00635-17
Department
Molecular Microbiology and Immunology