Phosphates Induced H-Type or J-Type Aggregation of Cationic Porphyrins with Varied Side Chains
| dc.contributor.author | Li, Zhiliang | |
| dc.contributor.author | Zeman, Charles J. | |
| dc.contributor.author | Valandro, Silvano | |
| dc.contributor.author | Bantang, Jose Paolo O. | |
| dc.contributor.author | Schanze, Kirk S. | |
| dc.date.accessioned | 2023-05-26T13:21:11Z | |
| dc.date.available | 2023-05-26T13:21:11Z | |
| dc.date.issued | 2023-05-16 | |
| dc.date.updated | 2023-05-26T13:21:12Z | |
| dc.description.abstract | Non-covalent interactions have been extensively used to fabricate nanoscale architectures in supramolecular chemistry. However, the biomimetic self-assembly of diverse nanostructures in aqueous solution with reversibility induced by different important biomolecules remains a challenge. Here, we report the synthesis and aqueous self-assembly of two chiral cationic porphyrins substituted with different types of side chains (branched or linear). Helical H-aggregates are induced by pyrophosphate (PPi) as indicated by circular dichroism (CD) measurement, while J-aggregates are formed with adenosine triphosphate (ATP) for the two porphyrins. By modifying the peripheral side chains from linear to a branched structure, more pronounced H- or J-type aggregation was promoted through the interactions between cationic porphyrins and the biological phosphate ions. Moreover, the phosphate-induced self-assembly of the cationic porphyrins is reversible in the presence of the enzyme alkaline phosphatase (ALP) and repeated addition of phosphates. | |
| dc.description.department | Chemistry | |
| dc.identifier | doi: 10.3390/molecules28104115 | |
| dc.identifier.citation | Molecules 28 (10): 4115 (2023) | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12588/1867 | |
| dc.rights | Attribution 4.0 United States | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | aggregation hydrolysis | |
| dc.subject | phosphates | |
| dc.subject | porphyrins | |
| dc.subject | self-assembly | |
| dc.title | Phosphates Induced H-Type or J-Type Aggregation of Cationic Porphyrins with Varied Side Chains | |
| dc.type | Article |