The Candida albicans Biofilm Matrix: Composition, Structure and Function

dc.contributor.authorPierce, Christopher G.
dc.contributor.authorVila, Taissa
dc.contributor.authorRomo, Jesus A.
dc.contributor.authorMontelongo-Jauregui, Daniel
dc.contributor.authorWall, Gina
dc.contributor.authorRamasubramanian, Anand K.
dc.contributor.authorLopez-Ribot, Jose L.
dc.date.accessioned2021-04-19T15:00:45Z
dc.date.available2021-04-19T15:00:45Z
dc.date.issued2017-03-08
dc.date.updated2021-04-19T15:00:45Z
dc.description.abstractA majority of infections caused by Candida albicans—the most frequent fungal pathogen—are associated with biofilm formation. A salient feature of C. albicans biofilms is the presence of the biofilm matrix. This matrix is composed of exopolymeric materials secreted by sessile cells within the biofilm, in which all classes of macromolecules are represented, and provides protection against environmental challenges. In this review, we summarize the knowledge accumulated during the last two decades on the composition, structure, and function of the C. albicans biofilm matrix. Knowledge of the matrix components, its structure, and function will help pave the way to novel strategies to combat C. albicans biofilm infections.
dc.description.departmentMolecular Microbiology and Immunology
dc.identifierdoi: 10.3390/jof3010014
dc.identifier.citationJournal of Fungi 3 (1): 14 (2017)
dc.identifier.urihttps://hdl.handle.net/20.500.12588/368
dc.rightsAttribution 4.0 United States
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectCandida albicans
dc.subjectcandidiasis
dc.subjectbiofilms
dc.subjectextracellular matrix
dc.subjectantifungal resistance
dc.titleThe Candida albicans Biofilm Matrix: Composition, Structure and Function
dc.typeArticle

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