An Abstracting Transformation for Amino Acid Polymorphism

At least within exons coding for proteins, we believe what is important is the sequence of amino acids produced, and because amino acids average about three possible codings, very different looking DNA sequences, S1 and S2, can code for precisely the same sequence of amino acids. This paper describes an abstracting transformation which replaces each letter in the DNA sequence with a single letter mask that can be matched instead, such that if S1 and S2 both code for the same sequence of amino acids their mask sequence will be identical. [...]