Enantioselectivity for Catalytic Cyclopropanation with Diazomalonates

Date

2003-03-24

Authors

Doyle, Michael
Hu, Wenhao

Journal Title

Journal ISSN

Volume Title

Publisher

ARKAT USA

Abstract

The use of chiral azetidinone-ligated dirhodium(II) catalysts activates dinitrogen extrusion from diazomalonates and provides access to cyclopropanation products with selectivities as high as 40-50% ee.

Description

Keywords

Cyclopropanation, diazomalonates, chiral catalysts, asymmetric synthesis

Citation

https://doi.org/10.3998/ark.5550190.0004.703

Department

Chemistry