SeTe nano-alloy for the regulation of redox reaction in cancer cells




Flores, Ernesto

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Nanomaterials are one of the most promising technologies of the 21st century. They are widely used in fields of science, health care, agriculture, technology, and industries. Their physical and chemical properties, such as magnetic, electrical, and optical, differentiate them from their bulk counterparts. These physical characteristics make them the focus of different scientific studies. The synthesis of nanomaterials is currently being studied due to the restrictions relevant to the translation of these materials from laboratory to fabrication. Pulse Laser Ablation in Liquids (PLAL) has been shown to be optimal. It is a versatile technique that allows the production of most nanomaterials, is low-cost and is environmentally friendly. To overcome the challenges of the oxidative effects of traditional liquid phases (water, acetone), we synthesized SeTe nanoalloys utilizing deep eutectic solvents with Ch-Cl as the hydrogen bond donor. The hydrogen bond acceptor is sugar-based to increase biocompatibility. We analyzed the size, shape, and charge of the nanomaterials to characterize the properties of SeTe. Our goal is to regulate redox activity in cancer cells by reducing the toxicity of SeTe by using Deep Eutectic Solvents. The use of this solvent as a liquid environment for pulse laser ablation was explored for the first time. Another key factor to consider ahead for the scalability of the system is the low cost of production of these deep eutectic solvents.



nanomaterials, cancer, deep eutectic solvent, undergraduate student works



Physics and Astronomy