Molecular analysis and pathogenicity of the Cladophialophora carrionii complex, with the description of a novel species

Simple item page
dc.contributor.authorde Hoog, G. S.
dc.contributor.authorNishikaku, A. S.
dc.contributor.authorFernandez-Zeppenfeldt, G.
dc.contributor.authorPadín-González, C.
dc.contributor.authorBurger, E.
dc.contributor.authorBadali, Hamid
dc.contributor.authorRichard-Yegres, N.
dc.contributor.authorvan den Ende, A. H. G. Gerrits
dc.creator.orcidhttps://orcid.org/0000-0002-6010-8414en_US
dc.date.accessioned2023-06-22T17:52:38Z
dc.date.available2023-06-22T17:52:38Z
dc.date.issued2007-06-01
dc.description.abstractCladophialophora carrionii is one of the four major etiologic agents of human chromoblastomycosis in semi-arid climates. This species was studied using sequence data of the internal transcribed spacer region of rDNA, the partial β-tubulin gene and an intron in the translation elongation factor 1-alpha gene, in addition to morphology. With all genes a clear bipartition was observed, which corresponded with minute differences in conidiophore morphology. A new species, C. yegresii, was introduced, which appeared to be, in contrast to C. carrionii, associated with living cactus plants. All strains from humans, and a few isolates from dead cactus debris, belonged to C. carrionii, for which a lectotype was designated. Artificial inoculation of cactus plants grown from seeds in the greenhouse showed that both fungi are able to persist in cactus tissue. When reaching the spines they produce cells that morphologically resemble the muriform cells known as the “invasive form” in chromoblastomycosis. The tested clinical strain of C. carrionii proved to be more virulent in cactus than the environmental strain of C. yegresii that originated from the same species of cactus, Stenocereus griseus. The muriform cell expressed in cactus spines can be regarded as the extremotolerant survival phase, and is likely to play an essential role in the natural life cycle of these organisms. Taxonomic novelty: Cladophialophora yegresii de Hoog, sp. nov.en_US
dc.description.departmentMolecular Microbiology and Immunologyen_US
dc.description.sponsorshipFondo Nacional de Investigaciones Cientificas y Tecnológicas (Fonacit), Venezuelaen_US
dc.identifier.citationde Hoog, G. S., Nishikaku, A. S., Fernandez-Zeppenfeldt, G., Padín-González, C., Burger, E., Badali, H., . . . van den Ende, A. H. G. G. (2007). Molecular analysis and pathogenicity of the Cladophialophora carrionii complex, with the description of a novel species. Studies in Mycology, 58(1), 219-234. doi:10.3114/sim.2007.58.08en_US
dc.identifier.issn0166-0616
dc.identifier.otherhttps://doi.org/10.3114/sim.2007.58.08
dc.identifier.urihttps://hdl.handle.net/20.500.12588/1928
dc.language.isoen_USen_US
dc.publisherElsevier; Westerdijk Fungal Biodiversity Instituteen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectcactusen_US
dc.subjectCladophialophoraen_US
dc.subjectchromoblastomycosisen_US
dc.subjectendophyteen_US
dc.subjectextremotoleranceen_US
dc.subjectphylogenyen_US
dc.subjecttaxonomyen_US
dc.titleMolecular analysis and pathogenicity of the Cladophialophora carrionii complex, with the description of a novel speciesen_US
dc.typeArticleen_US

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
de Hoog 2008 - Molecular analysis and pathogenicity of the Cladophialophora carrionii complex, with the description of a novel species.pdf
Size:
4.15 MB
Format:
Adobe Portable Document Format
Description:
Download

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.86 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

College of Sciences Faculty Research