Electronic Theses and Dissertations - UTSA Access Only

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This collection contains electronic UTSA theses and dissertations (ETDs), primarily from 2007 to present. The collection is not comprehensive; search the UTSA Library Catalog for a complete list of UTSA theses and dissertations.

These ETDs are available only to currently enrolled UTSA students, faculty or staff. To be able to download an ETD that is UTSA access only, navigate to “Log In” on the top right-hand corner of this screen, then select “Log in with my UTSA ID.”

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Former students are invited to broaden access to their thesis or dissertation by making it available in the Open Access collection. To initiate this process, or if you have any questions about the ETD collection, please contact rrpress@utsa.edu.

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    Social Vulnerability to Hurricane Disasters: Exploring the Effect of Place as a Mediating Factor
    (2018) Sanchez, Lorenzo Dean
    Research on social vulnerability to disasters has played an important role in the identification of factors that influence one’s ability to prepare for, respond to, cope with, and adapt to changing environmental conditions during the disaster life cycle. However, existing literature often fails to explore the effect of place as a significant dimension for vulnerability, and regards this as a separate consideration. This dissertation explores how social vulnerability is not a static construct over time, and considers place-based contexts as key components of the social vulnerability paradigm. Based on this approach, the main research questions for this dissertation concerns: Does social vulnerability operate differently across spatial contexts along the rural-urban continuum, how has vulnerability changed in the last 30 years, and how does vulnerability interact with place to influence disaster casualty risk outcomes differently for populations living in hurricane-prone areas along the Gulf and Atlantic coastal United States? In order to address these questions, this dissertation will examine the following three main research aims, which: 1) seeks to identify factors relative to social vulnerability with place-based considerations, which may predispose populations to higher or lower risks to hurricane-related disasters given spatial variations of place; 2) builds upon place-based social vulnerability, and seeks to identify how dynamic the concept is, and will attempt to identify areas with significant change via increasing or decreasing social vulnerability measurements over time and by type of place; and 3) seeks to determine if a relationship exists between disaster casualty risk and place-based dimensions of social vulnerability over time and across space. These aims are examined using several data sources: Integrated Public Use Microdata Series (IPUMS) - National Historical Geographic Information System (NHGIS, 1990 – 2010), Area Health Resource Files (2015 – 2016), and the Spatial Hazard Events and Losses Database for the United States (SHELDUS – 2017), which allow for an analysis of social vulnerability across time, place, and disaster-related outcomes. This dissertation has policy implications for emergency management practitioners, elected officials, public administrators, and disaster relief agencies to evaluate social vulnerability within their communities, recommendations for targeting at-risk populations with preparedness programs and policies, and provides a platform to re-evaluate traditional configurations of social vulnerability from a demographic approach to one that embraces socio-spatial and temporal considerations.
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    Professional development strategies to integrate technology into writing instruction
    (2009) Sanchez, Jacob
    The purpose of this study was to assess the technological methods available to writing teachers during professional development. The Local Writing Project (LWP) hosts a five week summer institute based on the writing workshop model for writing teachers from Pre-K-16. The design of the workshop is to share general writing knowledge, and this study focused on the possible integration of writing throughout the process. The technical aspects looked at the beliefs that teachers brought into the summer, the factors that play a role in integrating technology into curriculum, and how professional development can be adapted to help teachers integrate technology into their lessons. The findings included teachers' fears of technology, the factors related to teacher support systems and professional development unrelated to technology integration during a general summer in-service. Recommendations for future summer institutes include a Computer Instructional Technologist to help with the topics and computer set up, schedule the writing assignments to include technology throughout the summer, and offer communication support systems to help teachers on computer integration topics during the whole year.
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    A Variable Selection Algorithm for Creating Replicable Simple Structure Factor Solutions
    (2020) Sanchez, Michael Angel
    Factor analysis is commonly employed to identify and explore underlying factor structures. Unfortunately, when variable selection is involved, results often fluctuate across studies making it difficult to determine the "best" and most replicable factor structure. We propose a new factor analytic variable selection algorithm that examines the reproducibility, quality, and model fit of the factor solutions using training and validation subsamples. Observed variables are considered for removal sequentially from a factor structure based on commonly used statistical measures and practices in factor analysis, such as the magnitude of the primary and secondary loadings, model fit statistics, and under-representation of factors. This study also proposes a new statistic, known as the D-score, which measures the relative "distance" between the primary and secondary factor loadings and is used as part of the variable selection process. Using simulated data, this study explored the algorithm's performance across 108 samples from 36 factor structures varying in model complexity, interfactor correlation magnitudes (p = 0,.3,& .6) and sample size conditions (n = 300,500,& 1000). Overall, the algorithm's performance was a function of the model complexity, interfactor correlation, and sample size. Poor model performance often occurred with highly correlated factors, small sample sizes, and complex factor structures under the algorithm defaults. As with other variable selection algorithms, changes to the algorithm's criteria can yield increased (or decreased) model performance and change the final model selected. Implications and discussion of the algorithm's results are provided.
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    Behavioral Patterns of Kernel Level Rootkits Attacking Containers in Linux Environment
    (2017) Alexander, Nidhin Samuel
    Kernel Level Rootkits are a special category of malwares that has the capability to compromise operating system kernel and can hide itself from detection. With the advent of Linux Containers that share the kernel among them, kernel level rootkit becomes a critical threat. The main aim of this paper is to demonstrate the attack scenarios of kernel level rootkits affecting container environment and to provide behavioral specifications of these rootkits. We designed some sample kernel level rootkits to demonstrate the exploits of Linux Container. We then perform static analysis on the above samples and extract the malicious behavior. Behaviors collected from the rootkit samples are then fed as rules to a pattern matching tool to check for the specified malicious behavior with any object file on the system. We have implemented a prototype based on our behaviors and tested it on other rootkits. Experimental results indicate that our prototype is effective in detecting kernel level rootkits.
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    Elucidation of effector mechanisms that induce protective immunity against Francisella tularensis
    (2011) Sanapala, Shilpa
    Francisella tularensis is a Gram-negative coccobacillus and the etiological agent of the zoonotic disease tularemia. It is characterized by a facultative intracellular lifestyle and its ability to survive and proliferate within macrophages, hence evading extracellular immune surveillance mechanisms. The Francisella Pathogenicity Island (FPI) is a prominent virulence locus essential for phagosomal escape and cytosolic replication. Several genes have been identified to be important for phagosomal escape and intracellular growth. An FPI mutant DeltaiglB is deficient in phagosomal escape and is predicted to be processed within the phagosome through Class II pathway. On the other hand, Delta fopC, a mutant lacking the outer membrane lipoprotein FopC which is required for evasion of IFN-gamma mediated signaling, is speculated to escape into the cytosol and be processed through Class I pathway. This study examined the comparative protective efficacy of DeltaiglB and DeltafopC against pulmonary LVS challenge. Although the initial priming mechanism is different for the two mutants, vaccination with either strain offered protection in wild type mice and mice lacking Class I or Class II pathway mediators to a similar extent. However, Delta fopC vaccinated perforin knockout mice were markedly susceptible to the challenge. Greater bacterial burdens were also exhibited by Delta fopC vaccinated CD 8 knockout mice post LVS challenge. NK and T cells significantly killed LVS infected cells through cytotoxicity dependent pathway. Collectively, these results suggest that perforin in concert with granzyme is required for DeltafopC mediated immunity and both NK as well as T cells are involved in the cytolytic action.
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    Rooster Tails, Ranflas, and Rags: The Language and Literacy Practices of Latin Lowriders in San Antonio, TX
    (2017) Sanchez, Sonia N.
    This study sought to understand the meaning of literacy by examining the language and literacy practices found outside of academic institutions. By looking at the social practices of a lowrider community, multiple and diverse literacies were uncovered and made visible to outsiders of these non-mainstream communities. The focal participants in this study identified as Mexican, Hispanic, and Latina lowriders living in San Antonio, Texas. Three of the participants were members and presidents of local lowrider car clubs. The data for this study was gathered during a period of about five years and included participant observations, fieldnotes, interviews, and audio and video recordings collected during car shows, car club meetings, and social gatherings organized around cruises and hop offs. An analysis of documents and data was also conducted. The analysis of the data collected in this study revealed five themes that contributed to answering the research questions: (1) Literacy practices are patterned by social practices; 2) Digital tools such as Facebook and YouTube are purposeful; (3) Text is anything that involves meaning communicated through symbols that include spoken words (oral/written), actions, sounds, and images that members interpret according to their social and cultural contexts; (4) Lowrider identities are multiple and constructed through lowrider language, lowrider values, lowrider cars and bikes, and lowrider dress; and (5) Lowrider Discourses are mastered through apprenticeship. The five themes that emerged from the results of this study support literacy as always embedded within the social and cultural constructs of lowriding.
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    Effect of hydrogen bonding ability, dipole-dipole interactions and viscosity of extracellular matrix fluid on the bone mechanical behavior
    (2012) Samuel, Jitin
    This is an exploratory study to determine the role of water in sustaining the mechanical behavior of bone. Water is speculated to interact in two different ways with the mineral and collagen phases; namely, hydrogen bonding and dipole-dipole interactions. This study followed an experimental procedure of replacing water present in bone with different fluids of known hydrogen bonding abilities and polarities to identify effect of Hydrogen bonding and polarity of extracellular matrix fluid on the mechanical behavior of bone. After replacement of the extracellular matrix fluid with selected solvents, mechanical testing was done using a progressive loading protocol to determine the effect changing the hydrogen bonding ability and polarity of the matrix fluid on the mechanical behavior of bone. Further data processing to quantify the various parameters measuring different mechanical properties was done followed by statistical analysis to determine if there were any significant changes in the mechanical behavior of bone when the extracellular matrix fluid was replaced by other solvents. The experimental results indicated that there are significant changes in the bone mechanical behavior when the extracellular matrix fluid is replaced with different solvents.
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    Involvement in a first-year-experience course: What impact does it have on the collaboration between academic and student affairs professionals?
    (2013) Sanchez, Cheryl Lea
    The development of healthy relationships among the students, faculty, and staff at higher education institutions leads to the creation of a seamless, connected learning environment for the students (Blimling & Whitt, 1999; Kezar, Hirsch, & Burack, 2001; Kuh, Kinzie, Schuh, Whitt, & Associates, 2005; Pascarella & Terenzini, 2005). Nonetheless, the problem is that often the lack of collaboration between academic and student affairs professionals creates a barrier against the development of a campus climate that is conducive to meeting the learning needs of the students. Therefore, the purpose of this study was to explore the perceptions of academic and student affairs professionals at a rural, 2-year public Hispanic-Serving Institution (HSI) who were directly involved with the First-Year-Experience (FYE) course as to the impact that involvement had on the collaboration between the two departments, and consequently, the campus climate. A conceptual framework of Kezar's Model for Student and Academic Affairs Collaboration (2003) was utilized as a guide to this qualitative single case study, and data was collected via in-depth, semistructured interviews with six participants: three academic and three student affairs professionals. The interviews were transcribed and uploaded into NVivo 10 for data analysis. The analysis unveiled five themes: 1.) cross-institutional dialogue, 2.) leadership, 3.) cooperation, 4.) setting expectations, and 5.) creating a common vision. The participants' experiences indicated that the FYE was a supportive venue for enhancing cross institutional collaboration, which led to a more satisfying work environment, as well as a more supportive learning environment for the students.
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    Novel 3D nano-antennas of self-assembled zinc oxide on silver nanowires
    (2016) Sanchez, John Eder
    The manipulation of geometrical and structural arrangement of nano-devices, especially nanoantennas (nantennnas), is highly desirable for a precise controlling and monitoring of the multidirectional radiation pattern generated from the active elements on nanoantenna (nantenna) applications. Here we report the epitaxial growing of ZnO nanorods preferentially oriented along the [0001] direction on pentagonal faces (010) of Ag nanowires (Ag/ZnO). The Ag/ZnO nanosystem, resembling an hierarchal aerial antenna, was obtained using an innovative microwave irradiation process. There, the combination of chemical synthesis along accelerated micro wave irradiation digestion process, allows us to control precisely the morphology and distribution of the Ag/ZnO nanostructure. Because of the high order arrangement exhibited for the nanosystem as well as high rate of reproducibility in the production process, we opted to tested the nanostructures in a set of experiments ranging from the bulk properties down to in-situ nanoscale; in order to gain valuable information from the experiments and with the aim to give a real application to the nanomaterial. In this order, first, we described the far and near electric field generated for the nantenna obtained from electrical radiation patterns resulting from phase map reconstruction using off-axis electron holography. It is important to notice that knowing the properties at nanoscale level, it will give key insight of mechanism through which the metal-semiconductor (Ag-ZnO) behaves in opto-electronic applications. In fact, using electric numerical approximations methods for a finite number of ZnO nanorods on Ag nanowires it was shown that the electric radiation intensities maps match closely the experimental results obtained with electron holography. Additionally, to reinforce the understanding of how the metal-semiconductor (Ag-ZnO) nanostructures could be used as an active element on photo-signal reception/transmitter generation it was investigated the photo - catalytic activity by employing dynamic UV-vis spectrometry. There, it was determined a kinetic constant of photodegradation around k=0.0037 min-1 which is related with the capability of the nano-system to convert a photo-excitation signal onto a converted electrical stimulated signal. Moreover, studies of Raman spectroscopy shown the main activated vibrational modes corresponding to frequencies in the THz range, those were found to be characteristic of longitudinal and transversal modes with particularly two enhanced bands near to the infrared region (1200 cm-1) assigned to be optical overtones originated from the high ordered distribution contributing to the vibrational frequency of the whole system. Additionally, thermo-electric and electrical measurements were performed on the nanosystem ZnO NRs for testing the thermo-electrical properties by measuring the thermal coefficient of resistance (TCR) for the material in bulk. Particularly, for in-situ electrical measurements a single multi-pentagonal nanostructure of ZnO NRs was nano-manipulated to create a simple electrical circuit containing the nanostructure as a pasive element to measure directly the response current vs voltage to obtain the conductivity of the material by using emphin-situ TEM. Furthermore, because of the high directionality exhibited for the multi-pentagonal arrangement, studies of the growth mechanism along the active/contact faces of the heterojunction have been performed by mapping dynamical electron diffraction patterns under fin-situ precession electron diffraction (PED) to understand the coupling mechanism between the metal-semiconductor system. Indeed, the orientation phase maps, retrieved from PED, shown a preferential axis of growing (0001) of ZnO NRs along the expose faces (001) of silver nanowires. For completeness, x-ray diffraction in Brang-Bretano configuration shown the characteristic phases for both ZnO and Silver. The understanding of both opto-electronic properties as well as the mechanisms through which the contact metal-semiconductor behaves at nanoscale level undoubtedly will allow us to elucidate the receiving/transmitting mechanism on future nanoantennas applications.
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    A Celebration of Military Music in Military City, USA
    (2020) Samuel, Joseph Victor
    This recital document summarizes and expands upon the information provided in the lecture portion of my graduate lecture-recital, presented on November 20th, 2019, in a concert billed as "A Celebration of Military Music in Military City, USA!" The first chapter contains a historical summary of the purpose of music in the military with an emphasis on the role of music in the U.S. Army since World War I to the current time. The second chapter will focus on Alfred Reed's military service and the circumstances surrounding the composition of Russian Christmas Music. The third chapter will explore the life of John Barnes Chance, the composition of Variations on a Korean Folksong, and the many similarities between his military service and my own. The fourth chapter will focus on the heritage of the 191st Army Band and the composition of my original work, Dublin's Sword, which I composed for that band. The final chapter provides my reflections as a military musician on the continuing importance of music as a significant element in the mission of the U.S. Army.
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    Longitudinal distribution of homicide in the city of San Antonio, TX: Trends, patterns and theory
    (2009) Romero, Fabian S.
    Homicide is one of the best indicators of violence. Homicide, like other forms of physical violence, tends to cluster in hotspots within urban areas. This thesis is a case study of the homicide patterns in San Antonio, TX. The purpose is to identify trends, patterns, and theoretical explanations that may account for these patterns. Some of the factors analyzed are: social and economic determinants, demographics, and multiple characteristics disadvantaged and deprived neighborhoods. Longitudinal data on San Antonio homicides and social factors compiled by Dr. Michael Gilbert for the period from 1988 to 2002 will provide a foundation for this project. The method of Ordinary Least Squares (OLS) multiple regression was used during the analysis. Findings indicated a consistent correlation between the level of multiple deprivations experienced in disadvantaged census tracts and homicides. As anticipated, economic disadvantages were significantly more important as a single predictor of violence. However, residential instability or variables used to measure family disruption, did not produce an important effect on homicide rates.
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    Maintaining high performance in the QR factorization while scaling both problem size and parallelism
    (2011) Samuel, Siju
    QR factorization is an extremely important linear algebra operation used in solving multiple linear equations, particularly least-square-error problems, and in finding eigenvalues and eigen-vectors. This thesis details the author's contributions to the field of computer science by providing performance-efficient QR routines to ATLAS (Automatically Tuned Linear Algebra Software). ATLAS is an open source linear algebra library, intended for high performance computing. The author has added new implementations for four types/precisions (single real, double real, single complex, and double complex) in four different variants of matrix factorization (QR, RQ, QL and LQ). QR factorization involves a panel factorization and a trailing matrix update operation. A statically blocked algorithm is used for the full matrix factorization. A recursive formulation is implemented for the QR panel factorization, providing more robust performance. Together these techniques result in substantial performance improvement over the LAPACK version.
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    A Phenomenological Study Investigating the Experiences of Refugee Adolescents' Transition into the Culture of the United States of America
    (2018) Sampson, Seth A.
    Refugee adolescents have experiences that affect their social identities and shape their abilities to successfully acculturate into a new society (Sirin, Ryce, Gupta, & Rogers-Sirin, 2013). The dual pressures of acculturation and serving as a link between their family and their new country magnify these adolescent refugees' difficulties in adjusting to school and work (Porte & Torney-Puerta, 1987; Sack, Angell, Kinzie, & Rath, 1986, as cited in Lese & Robbins, 1994). This study, which highlights how the transition may affect adolescent refugees' abilities to form sustainable and meaningful relationships, is intended to be a stepping stone upon which counselors and researchers in both the education and clinical fields can build. Social identity theory, social constructivist theory, and cultural identity theory will serve as a framework for inquiry.
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    Nanomechanics of Human Bone: In Situ Deformation Characterization Using Synchrotron X-Ray Scattering and Pole Figure Inversion Techniques
    (2018) Samuel, Jitin
    Bone is a highly hierarchical material with different structural features encompassing macro to ultrastructural length scales. Bone toughness is understood to originate at the ultrastructural level where the primary architectural feature is one resembling a hybrid nano-composite of an organic matrix comprised mainly of type-I collagen and mineral crystals intertwined with non-collagenous proteins in the presence of water. Understanding the fundamental features of bone at the ultrastructure and their contributions to the bulk behavior is imperative in understanding mechanistic origins of bone fragility at ultrastructural changes levels induced by skeletal disorders and aging. The mineral phase in bone is highly textured, most likely due to the functional adaptations of the tissue under load, as the mineral crystals are the primary load bearing components of the tissue. Such textured structures contribute to anisotropy of bone tissues, as seen in polycrystalline materials. Another interesting ultrastructural feature of bone is that the mineral crystals can be distinctive based on their spatial location in the matrix. It has been reported that minerals residing inside collagen fibrils show staggered plate-like structures and are preferentially oriented along the longitudinal axis of collagen fibrils, whereas the minerals residing outside the fibrils possess very limited spatial correlations. It is still unclear how the minerals at distinct ultrastructural locations influence the tissue level deformation of bone. The ultrastructural stresses in mineral and collagen phases are not consistent with the bulk stress of bone due to the complex architecture of bone. Mineral crystals are inherently anisotropic and the contribution of each crystal to the bulk deformation is orientation dependent. In addition, the intrafibrillar and extrafibrillar differences further exacerbate the difficulty in explaining the mechanistic origins of bone fragility at ultrastructure levels. Such complexity of bone architecture has made it very challenging to experimentally evaluate the mechanical behavior of bone at ultrastructural levels. So far, the work in this field has been limited to computational modeling based approaches or to experimental characterization using highly simplified models. However, such models are not capable of capturing the contribution of intrafibrillar and extrafibrillar minerals to the anisotropy and in situ mechanical behavior of bone. In this study, we propose a semi-empirical approach to characterize the in situ strains and stresses of the mineral phase in the distinctive ultrastructural locations using synchrotron X-ray diffraction techniques and optimization-based texture analysis and strain characterization techniques.
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    Towards understanding and improving gait rehabilitation in virtual environments using latency for persons with mobility impairments
    (2015) Samaraweera, Gayani
    Latency is an unavoidable byproduct of the modern virtual reality systems. Although it has been highly studied for several decades, the effects of latency and how it is perceived by persons suffering from mobility impairments have not been investigated. It is important to understand the effects latency has on such under-investigated populations (e.g. persons suffering from Multiple Sclerosis) with the increasing use of virtual reality technology in physical rehabilitation techniques. Therefore, the first study was conducted aiming at understanding the influences of latency and the presence of an avatar have on persons suffering from mobility impairments. The results showed that most participants failed to notice even the higher latency conditions present in the virtual environment, even though their gait was altered. To investigate the lack of latency detection noted, a second study was carried out to examine how the latency thresholds of participants suffering from Multiple Sclerosis may differ from healthy participants. The results showed considerably higher tolerance for latency in participants suffering from multiple sclerosis than healthy participants. Thus, I raised the following question: "can latency be used to create a perceptual illusion to effectively improve rehabilitation in persons suffering from mobility impairments?" To investigate, I conducted two additional experiments where differing latency levels are applied to the left and right side of a self-avatar with both healthy and participants with mobility impairments. The results showed the potential of manipulating walking patterns using latency in a virtual environment. Here, I report the results of these experiments and the implications they have in general virtual rehabilitation system design as well as gait rehabilitation for asymmetric gait. Latency can thus be potentially used as a gait altering technique in a virtual environment.
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    Bacteria Balancing Act: Exploring the Association of Social and Sexual Dynamics on the Primate Microbiome in Pan paniscus and Colobus vellerosus
    (2023) Samartino, Shelby D.
    This dissertation examines the relationship between social and sexual behaviors and microbiota composition in two primates: the bonobo (Pan paniscus) and black-and-white colobus (Colobus vellerosus). I collected behavioral data and vaginal swabs over a 21-day period at Ape Cognition and Conservation Initiative in Des Moines, IA. Vaginal microbiota composition was not predicted by individual ID, but there was a trend of significant effect of swelling size and sexual interactions. I also utilized a dataset of urinary cortisol samples collected during the same study period to examine the association between vaginal microbiota diversity and cortisol. I identified a strong trend towards a positive relationship between alpha diversity and cortisol level for one female when samples were collected on the same day, but this same relationship was not observed in the other female. I investigated whether social instability associated with the immigration of new males could explain differences in the gut microbiota in female colobus across several social groups at Boabeng-Fiema, Ghana. Beta diversity was predicted by year, alpha male stability, group identity, age, and individual ID. I then utilized focal follow data of 19 adult females to create 1-m proximity networks. Yearly 1-m proximity ties predicted female beta-diversity in socially stable groups. An alpha male takeover in the third group was associated with infant mortality and temporal variation in proximity networks. Findings from this dissertation provide evidence for how different external factors are associated with vaginal microbiota composition in bonobos and how the conditions surrounding alpha male instability predict gut microbiota composition in colobus. Overall, my results suggest social and sexual transmission of microbes both shapes and is shaped by behavior, making further investigation vital to understanding their role in the evolution of group living.
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    Identifying and Quantifying Molecular Species in Biological Samples Using a Multimodal Mass Spectrometry Approach
    (2021) Samenuk, Grace Marie
    Mass spectrometry is a versatile analytical tool that can identify, quantify, and even localize an analyte in biological samples. Mass spectrometry has a plethora of applications, but it is often underutilized in fields outside of analytical chemistry. Through optimized method development and utilization of other techniques, multidisciplinary results can be obtained. Cattle fever ticks pose an impending threat to the United States. Through mass spectrometry, current approved macrocyclic lactone-based drugs are quantified using electrospray ionization liquid chromatography tandem mass spectrometry (ESI-LC/MS/MS). The results are used to make recommendations concerning interactions, and efficacy. Additionally, novel drug-targets are probed though matrix-assisted laser desorption/ionization time-of flight mass spectrometry imaging (MALDI-TOF MSI). Peptides are localized and identified on intact tissue sections of cattle fever ticks. The methodology allows for interspecies comparisons, and investigation into mechanisms for drug-resistance. Mass spectrometry can be applied to analysis of other biological matrices. Fatty acid content in skin, and plasma samples can be quantified, and correlated to self-reported pain. The higher the omega-6 fatty acid content, the more sensitive one is to external stimuli. Therefore, the ratio of omega-6 to omega-3 fatty acids are shown to influence pain mechanism pathways, and may contribute to comorbid pain conditions, such as diabetic neuropathy. Aged, dried blood spots contain viable information but are often overlooked. Through optimized sample prep, proteins can be extracted and identified. This provides a baseline for comparison to changes in protein compositions after potential diseases progression. This work bridges the gap between multiple disciplines for more rounded research.
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    Analysis of the interaction between Arabidopsis ERF13, WRKY33 and the TGMV AL1629 promoter
    (2012) Samant, Neha Shirish
    Tomato Golden Mosaic virus (TGMV), a member of the Geminiviridae family of plant-infecting DNA viruses, is able to interact with different host factors to regulate its gene expression. The TGMV AL2 protein is a transcriptional activator, encoded by the AL1629 complementary sense transcript. My research focuses on the TGMV AL1629 promoter and its interaction with Arabidopsis transcription factors. It has been previously reported that a host factor, Ethylene Response Factor 13 (AtERF13) binds to a specific nine base pair sequence (AACGTCATC) within the TGMV AL1629 promoter. My results demonstrate that AtERF13 interacts with the TGMV AL1629 promoter in vivo using Chromatin Immunoprecipitation (ChIP). ERFs are transcription factors that are induced upon external stimuli including viral challenge, and I have shown ERF13 is induced upon TGMV infection within 24 hours, after which expression levels decrease as over time. This suggests that induction of ERF by geminivirus infection is an early response. Although ERFs appear to bind to GCC box sequences within promoters, the TGMV AL1629 promoter lacks such a sequence element. However, Tomato ERF Pti4 interacts with both GCC as well as non-GCC containing promoter sequences. This suggests the possibility that ERFs may interact with promoters in conjunction with other host factors. My studies have revealed an interaction between AtERF13 and AtWRKY33, another plant transcription factor that plays a role in the positive regulation of transcription. This work suggests that a complex consisting of AtERF13 and AtWRKY33 may regulate the geminivirus AL1629 promoter to activate AL2 gene expression. Together these results indicate that geminiviruses may target proteins induced in response to infection for regulation of viral genes. Disrupting interactions between virus and host could provide a way to develop resistance strategies against this devastating group of plant viruses.
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    A high level synthesis of GPS acquisition
    (2014) Samudrala, Madhuri
    With increasing complexity of system on chip designs, it is becoming harder to generate register transfer level structure. High level synthesis tools have become the tool of choice for designing ASSIC/FPGA's. A High level synthesis tool converts the algorithmic specification of a digital system to register transfer level (RTL). This thesis talks in detail on how a High level synthesis tool simplifies the design of large & complex hardware thereby improving the speed of a GPS Acquisition. Main goal of this research is to improve the performance of a GPS Acquisition by converting the algorithm code of the respective design to RTL design Algorithm.
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    Graduate instrumental conducting recital document
    (2017) Saltibus, Matthew Bernard
    This document explores four different pieces of music, with the information used to enhance and provide knowledge when performed in recital. It first expresses the significance and the important role of the viola through Telemann's Viola Concerto in G Major. It also provides historical evidence that may lead one to question the name of the instruments in the 'violin family.' Particular attention is given to the history of the viola and the concerto. Secondly, historical context provides evidence of eighteenth-century performance practices, which can be used to perform Wolfgang Amadeus Mozart's Piano Concerto No. 20 in D Minor. Particular attention is given to the standard violin playing techniques in the eighteenth century. The third work, Robert Fuchs' Serenade No. 3 in E Minor, provides historical information about the role of the conductor. Conducting considerations are explored in his first and third movements. Lastly, the work of Benjamin Britten's Simple Symphony is examined and analyzed. Particular attention is given to the main themes of each movement. Each theme contains historical information provided by Britten himself.